abstract：BACKGROUND:Type 2 diabetes and its management affect the patient and the close family potentially causing either psychological distress or increased sense of responsibility and collaboration in these families. Interactions between patient and family play an important role in maintaining lifestyle changes and diabetes s...

journal_title：Diabetology & metabolic syndrome

authors： Bennich BB,Røder ME,Overgaard D,Egerod I,Munch L,Knop FK,Vilsbøll T,Konradsen H

更新日期：2017-07-21 00:00:00

abstract：OBJECTIVE:To translate and validate the instrument Diabetes Self-Management Profile (DSMP)-Conventional and Flexible Regimens into Brazilian Portuguese language in order to evaluate the quality of diabetes self-management in children and adolescents with type 1 diabetes and their caregivers. METHODS:DSMP was submitted...

journal_title：Diabetology & metabolic syndrome

authors： Passone CGB,Esteves LSO,Savoldelli RD,Harris MA,Damiani D,Manna TD

更新日期：2017-07-11 00:00:00

abstract：BACKGROUND:Dipeptidyl peptidase-4 (DDP4) is an enzyme responsible for glucagon-like peptide-1 inactivation and plays an important role in glucose metabolism. OBJECTIVE:The aim of this study was to evaluate DPP4 levels in patients with familial partial lipodystrophy type 2 (FPLD2) and correlate it with body fat distrib...

journal_title：Diabetology & metabolic syndrome

authors： Valerio CM,de Almeida JS,Moreira RO,Aguiar LBS,Siciliano PO,Carvalho DP,Godoy-Matos AF

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:Many self-management programs have been developed so far. Their effectiveness varies. The program 'Beyond Good Intentions' (BGI) is based on proactive coping and has proven to be (cost-) effective in achieving reductions in BMI and blood pressure in screen-detected type 2 diabetes patients up until nine mont...

journal_title：Diabetology & metabolic syndrome

authors： Vos RC,Eikelenboom NW,Klomp M,Stellato RK,Rutten GE

更新日期：2016-12-20 00:00:00

abstract：BACKGROUND:Increased carotid intima-media thickness (CIMT), a marker of subclinical atherosclerosis, is an independent predictor of future cardiovascular events, and has been reported in children with various chronic diseases, including type 1 diabetes mellitus (DM1). OBJECTIVES:Evaluate CIMT and its association with ...

journal_title：Diabetology & metabolic syndrome

authors： Fusaro MF,Zanini JL,Silva IN

更新日期：2016-11-11 00:00:00

abstract：BACKGROUND:We investigated the effect of longitudinal status change in metabolic syndrome (MetS) assessed by two different criteria on new onset of type 2 diabetes (NODM) in a Japanese population. METHODS:The participants were 827 non-diabetic citizens who had undergone medical examinations in 1994 and 2003 or 2004. W...

journal_title：Diabetology & metabolic syndrome

authors： Ohnishi H,Saitoh S,Akasaka H,Furukawa T,Mori M,Miura T

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:Adherence to treatment has been defined as the degree to which a patient's behavior corresponds to medical or health advice; however, the most appropriate method to evaluate adherence to diabetes care has yet to be identified. We conducted analyses to compare adherence assessments and blood glucose monitorin...

journal_title：Diabetology & metabolic syndrome

authors： Telo GH,de Souza MS,Andrade TS,Schaan BD

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus (DM) globally affects 18-20 % of adults over the age of 65 years. Diabetic kidney disease (DKD) is one of the most frequent and dangerous complications of DM2, affecting about one-third of the patients with DM2. In addition to the pancreas, adipocytes, liver, and intestines, the kidn...

journal_title：Diabetology & metabolic syndrome

authors： Pecoits-Filho R,Abensur H,Betônico CC,Machado AD,Parente EB,Queiroz M,Salles JE,Titan S,Vencio S

更新日期：2016-07-28 00:00:00

abstract：BACKGROUND:Helicobacter pylori (H. pylori) infection is reported to be associated with various extragastrointestinal conditions such as insulin resistance, diabetes mellitus and metabolic syndrome. H. pylori infection and type 2 diabetes mellitus (T2DM) are associated with oxidative stress, this cross-relation between ...

journal_title：Diabetology & metabolic syndrome

authors： Nasif WA,Mukhtar MH,Nour Eldein MM,Ashgar SS

更新日期：2016-05-03 00:00:00

abstract：BACKGROUND:Dietary factors are important environmental factors associated with the prevalence of metabolic syndrome (MS). The objective of this study was to assess the habitual nutrient intakes of patients with MS. METHODS:A cross-sectional study included 103 patients (82 % women) with MS seen at the endocrinology out...

journal_title：Diabetology & metabolic syndrome

authors： da Cunha AT,Pereira HT,de Aquino SL,Sales CH,Sena-Evangelista KC,Lima JG,Lima SC,Pedrosa LF

更新日期：2016-04-14 00:00:00

abstract：BACKGROUND:Distal symmetric polyneuropathy (DSPN) is the most common complication of type 2 diabetes mellitus (T2DM) and the most common form of peripheral neuropathy. DSPN increases the risk of foot ulceration up to seven-fold, and is a significant risk factor in more than 60 % of the amputations of the lower limbs in...

journal_title：Diabetology & metabolic syndrome

authors： Timar B,Popescu S,Timar R,Baderca F,Duica B,Vlad M,Levai C,Balinisteanu B,Simu M

更新日期：2016-04-11 00:00:00

abstract：BACKGROUND:Polymorphisms of vitamin D receptor (VDR) gene have been studied as genetic markers of type 1 diabetes mellitus (T1DM) and some studies have reported associations with autoimmune thyroid disease. The aim of this study was to evaluate the relationship between VDR FokI polymorphism (rs10735810), thyroid autoim...

journal_title：Diabetology & metabolic syndrome

authors： Mory DB,Gabbay MA,Rocco ER,Kasamatsu T,Crispim F,Miranda WL,Dib SA

更新日期：2016-03-22 00:00:00

abstract：BACKGROUND:Sex hormone-binding globulin (SHBG) has been proposed as a biomarker of MetS in children and adults. We aim to determine the associations of SHBG with components of MetS in children from the Middle-East where the prevalence of MetS are on the rise. METHODS:In this cross-sectional study, a total of 509 rando...

journal_title：Diabetology & metabolic syndrome

authors： Al-Daghri NM,Khan N,Sabico S,Al-Attas OS,Alokail MS,Kumar S

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:In most individuals, obesity and insulin resistance coexist. However, some individuals have excessive adipose tissue mass but remain insulin sensitive. Moreover, lean individuals can develop acute inflammation-induced insulin resistance, even without excess adipose tissue mass. OBJECTIVE:Our aim was to comp...

journal_title：Diabetology & metabolic syndrome

authors： Moscavitch SD,Kang HC,Filho RA,Mesquita ET,Neto HC,Rosa ML

更新日期：2016-02-09 00:00:00

abstract：BACKGROUND:Diabetic retinopathy is the main cause of preventable blindness in the economically active population in western countries. Diabetic retinopathy screening is effective in preventing blindness and can be performed through various diagnostic methods. Our objective is to compare binocular indirect ophthalmoscop...

journal_title：Diabetology & metabolic syndrome

authors： Malerbi FK,Morales PH,Farah ME,Drummond KR,Mattos TC,Pinheiro AA,Mallmann F,Perez RV,Leal FS,Gomes MB,Dib SA,Brazilian Type 1 Diabetes Study Group.

更新日期：2015-12-21 00:00:00

abstract：BACKGROUND:Using patient data from the GetGoal-Duo1, -L, and L-Asia trials, the objectives of this study were to evaluate and compare the impact of lixisenatide once-daily add-on treatment to basal insulin therapy ±oral antidiabetic drugs (OADs) among type 2 diabetes (T2DM) patients subdivided into groups, based on the...

journal_title：Diabetology & metabolic syndrome

authors： Eto K,Naito Y,Seino Y

更新日期：2015-11-21 00:00:00

abstract：BACKGROUND:Number of diabetic patients under public primary care in Hong Kong rose from 150,157 (2009) to 173,015 (2013). This study aimed to track the 5-year change of their outcomes and care standard after the introduction of quality enhancement programmes. METHODS:Longitudinal study was conducted on a group of diab...

journal_title：Diabetology & metabolic syndrome

authors： Fung CS,Wan EY,Jiao F,Lam CL

更新日期：2015-09-17 00:00:00

abstract：BACKGROUND:Vildagliptin, a DPP-4 inhibitor widely used for the treatment of type 2 diabetes mellitus (T2DM), shows beneficial effects on endothelial function. This study aims to evaluate the effect of vildagliptin on endothelial function and arterial stiffness in patients with T2DM and hypertension. METHODS:Fifty over...

journal_title：Diabetology & metabolic syndrome

authors： Cosenso-Martin LN,Giollo-Júnior LT,Martineli DD,Cesarino CB,Nakazone MA,Cipullo JP,Vilela-Martin JF

更新日期：2015-08-26 00:00:00

abstract：BACKGROUND:Diabetes treatment requires specialized multi-professional teams, supplies for blood glucose monitoring and training for self-injections of human insulin or insulin analogues. The State Health Secretariat of the Federal District (SHS-FD) has dispensed insulin analogues by means of clinical validated protocol...

journal_title：Diabetology & metabolic syndrome

authors： Leite EB,Pedrosa HC,Casulari LA

更新日期：2015-08-18 00:00:00

abstract：:The development of extended-action insulin analogues was motivated by the unfavorable pharmacokinetic (PK) profile of the conventional long-acting insulin formulations, generally associated with marked inter and intra patient variability and site- and dose-dependent effect variation. The new ultra-long insulin analogu...

journal_title：Diabetology & metabolic syndrome

authors： Tambascia MA,Eliaschewitz FG

更新日期：2015-06-26 00:00:00

abstract：BACKGROUND:In mammals, the temperature rhythm is regulated by the circadian pacemaker located in the suprachiasmatic nuclei, and is considered a "marker rhythm". Melatonin, the pineal gland hormone, is a major regulator of the endogenous rhythms including body temperature. Its production is influenced by many factors, ...

journal_title：Diabetology & metabolic syndrome

authors： Ramos-Lobo AM,Buonfiglio DC,Cipolla-Neto J

更新日期：2015-04-29 00:00:00

abstract：BACKGROUND:Polymorphisms in genes encoding adiponectin (ADIPOQ) and interleukin-6 (IL6) have been associated with adiposity and obese-related phenotypes. This study investigated the relationship of ADIPOQ and IL6 gene polymorphisms with pro-inflammatory and cardiometabolic markers in obese patients. METHODS:Anthropome...

journal_title：Diabetology & metabolic syndrome

authors： de Oliveira R,Moraes TI,Cerda A,Hirata MH,Fajardo CM,Sousa MC,Dorea EL,Bernik MM,Hirata RD

更新日期：2015-04-11 00:00:00

abstract：BACKGROUND:Pregnant women with mild gestational hyperglycemia present a high risk for hypertension and obesity, and appear to reproduce the model of metabolic syndrome in pregnancy, including hyperinsulinemia and insulin resistance. Diabetic patients have a higher frequency of the IRS-1 Gly972Arg variant and this polym...

journal_title：Diabetology & metabolic syndrome

authors： Gelaleti RB,Damasceno DC,Salvadori DM,Marcondes JP,Lima PH,Morceli G,Calderon IM,Rudge MV

更新日期：2015-04-02 00:00:00

abstract：:Women diagnosed with gestational diabetes mellitus have an increased risk of developing diabetes mellitus, which is a known risk factor for cardiovascular disease and insulin resistance. In the recently published article by Zajdenverg et al., they aimed to identify endothelial dysfunction and cardiovascular risk facto...

journal_title：Diabetology & metabolic syndrome

authors： Kayadibi H,Sertoglu E,Uyanik M

更新日期：2015-03-19 00:00:00

abstract：OBJECTIVE:To study the clinical and molecular characteristics of a sample of Brazilian patients with Congenital Hyperinsulinemic Hypoglycemia (CHH). METHODS:Electronic message was sent to members from Endocrinology Department- Brazilian Society of Pediatrics requesting clinical data for all cases of CHH. A whole blood...

journal_title：Diabetology & metabolic syndrome

authors： Del Roio Liberatore R Jr,Ramos PM,Guerra G Jr,Manna TD,Silva IN,Martinelli CE Jr

更新日期：2015-02-18 00:00:00

abstract：BACKGROUND:Visceral adiposity contributes to cardiometabolic risk, and visceral adiposity index (VAI) had significant correlation with visceral adiposity. We aimed to explore whether VAI was associated with cardiac structure and function and assess the impact of the cut-off points of VAI defining visceral adipose dysfu...

journal_title：Diabetology & metabolic syndrome

authors： Han L,Fu KL,Zhao J,Wang ZH,Tang MX,Wang J,Wang H,Zhang Y,Zhang W,Zhong M

更新日期：2014-12-22 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) is a major cardiovascular complication in diabetic patients. Despite the significant association between obesity and diabetes, the majority of the diabetic subjects are not obese in an Asian population. This study evaluated the association between obesity and coronary artery dis...

journal_title：Diabetology & metabolic syndrome

authors： Won KB,Chang HJ,Niinuma H,Sung J,Cho IJ,Shim CY,Hong GR,Kim YJ,Choi BW,Chung N

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:Type 1 diabetes mellitus in pregnant women is associated with an increased risk of congenital malformations, obstetric complications, neonatal morbidity, and mortality. Our aim was to evaluate which factors from the first trimester of pregnancy have a significant impact on the pregnancy outcomes of women wit...

journal_title：Diabetology & metabolic syndrome

authors： Timar B,Timar R,Albai A,Stoian D,Nitu R,Craina M

更新日期：2014-11-22 00:00:00

abstract：BACKGROUND:The objective was to evaluate the muscle glucose metabolism in rats fed a fructose-rich diet after fetal protein malnutrition, at rest and after acute physical exercise at maximal lactate steady-state intensity. METHODS:The male offspring born of mothers fed on a balanced or low-protein diet were split in f...

journal_title：Diabetology & metabolic syndrome

authors： Cambri LT,Ribeiro C,Botezelli JD,Ghezzi AC,Mello MA

更新日期：2014-11-06 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor of nitric oxide (NO) synthetase. Elevated ADMA reduces NO formation and is associated with endothelial dysfunction. The aims of this study were to evaluate endothelial function and the cardiovascular risk (CVR) profile in patients with...

journal_title：Diabetology & metabolic syndrome

authors： Sayki Arslan M,Turhan S,Dincer I,Mizrak D,Corapcioglu D,Idilman R

更新日期：2014-10-14 00:00:00

abstract：BACKGROUND:Galectin-3 is a family of soluble beta-galactoside-binding lectins that play many important regulatory roles in inflammation. Galectin-3-deficient mice have been shown to exhibit excess adiposity, hyperglycemia, insulin resistance and systemic inflammation. We investigated the association between serum galec...

journal_title：Diabetology & metabolic syndrome

authors： Ohkura T,Fujioka Y,Nakanishi R,Shiochi H,Sumi K,Yamamoto N,Matsuzawa K,Izawa S,Ohkura H,Ueta E,Kato M,Miyoshi E,Taniguchi S,Yamamoto K

更新日期：2014-09-27 00:00:00

abstract：BACKGROUND:Patients with either diabetes mellitus (DM) or metabolic syndrome (MS) are recognized as a high risk group for cardiovascular disease (CVD). Several studies have demonstrated the clinical value of MS for predicting additional CVD risk in the DM population, although the clinical significance remains debatable...

journal_title：Diabetology & metabolic syndrome

authors： Rhee SY,Park SY,Hwang JK,Son JI,Chin SO,Kim YS,Woo JT

更新日期：2014-09-12 00:00:00

abstract：BACKGROUND:Liraglutide, a glucagon-like peptide-1 (GLP-1) analogue, has been shown to possess pleiotropic effects including body weight reduction. However, long-term effect of liraglutide on body weight and glycemic control has not been elucidated in Japanese type 2 diabetes (T2D) subjects. Present study investigates w...

journal_title：Diabetology & metabolic syndrome

authors： Inoue K,Maeda N,Fujishima Y,Fukuda S,Nagao H,Yamaoka M,Hirata A,Nishizawa H,Funahashi T,Shimomura I

更新日期：2014-09-08 00:00:00

abstract：BACKGROUND:The clinical features of atherosclerotic lesions in ketosis-onset diabetes are largely absent. We aimed to compare the characteristics of lower limb atherosclerotic lesions among type 1, ketosis-onset and non-ketotic type 2 diabetes. METHODS:A cross-sectional study was performed in newly diagnosed Chinese p...

journal_title：Diabetology & metabolic syndrome

authors： Li MF,Ren Y,Zhao CC,Zhang R,Li LX,Liu F,Lu JX,Tu YF,Zhao WJ,Bao YQ,Jia WP

更新日期：2014-06-03 00:00:00

abstract：BACKGROUND:The oral DPP-4 inhibitors are new incretin-based therapies for treatment of type 2 diabetes. To assess the efficacy and safety of three DPP-4 inhibitors (Saxagliptin, Sitagliptin and Vildagliptin) as add-on therapy to dual combination of traditional oral hypoglycemic agents in Chinese type 2 diabetes patient...

journal_title：Diabetology & metabolic syndrome

authors： Li CJ,Liu XJ,Bai L,Yu Q,Zhang QM,Yu P,Yu DM

更新日期：2014-05-31 00:00:00

abstract：BACKGROUND:The vascular complications of outpatients with diabetes at ordinary hospitals vary. Ischemic heart disease is barely predictable after treatment using previously reported therapeutic indices. We developed a simple and noninvasive screening method to evaluate the possibility of ischemic heart disease in patie...

journal_title：Diabetology & metabolic syndrome

authors： Kajimoto T,Sawamura MS,Hayashi RD,Oya T,Hirao RA,Kouhara H

更新日期：2014-04-08 00:00:00

abstract：BACKGROUND:Many patients with chronic heart failure (CHF) are believed to have unrecognized diabetes, which is associated with a worse prognosis. This study aimed to describe glucose tolerance in a general stable CHF population and to identify determinants of glucose tolerance focusing on body composition and skeletal ...

journal_title：Diabetology & metabolic syndrome

authors： Stevens AL,Hansen D,Vandoren V,Westerlaken R,Creemers A,Eijnde BO,Dendale P

更新日期：2014-03-27 00:00:00

abstract：:Insulin resistance and hypertension are considered as prototypical "diseases of civilization" that are manifested in the modern environment as plentiful food and sedentary life. The human propensity for insulin resistance and hypertension is a product, at least in part, of our evolutionary history. Adaptation to ancie...

journal_title：Diabetology & metabolic syndrome

authors： Zhou MS,Wang A,Yu H

更新日期：2014-01-31 00:00:00

abstract：BACKGROUND:The single-center, open-label, four-arm, exploratory study investigates the relation of different anti-diabetics to serum levels of active TGF-β, a known pro-fibrotic stimulus, before and after a defined test meal. FINDINGS:We investigated sera of patients with type 2 diabetes mellitus (T2DM) treated with m...

journal_title：Diabetology & metabolic syndrome

authors： Pscherer S,Freude T,Forst T,Nussler AK,Braun KF,Ehnert S

更新日期：2013-08-31 00:00:00

abstract：BACKGROUND:The aim of this study is to compare the efficacy of intensification of insulin treatment with insulin glargine and biphasic human insulin in patients with type 2 diabetes on concomitant therapy with oral antidiabetic drugs (OAD) in daily clinical practice. METHODS:A retrospective multicentre parallel two-ar...

journal_title：Diabetology & metabolic syndrome

authors： Tentolouris N,Kyriazopoulou V,Makrigiannis D,Baroutsou B

更新日期：2013-08-05 00:00:00